CAS RN: 129-06-6 | Product Number: W0005
Warfarin Sodium (contains Isopropyl Alcohol)
|Size||Unit Price||Philadelphia, PA||Portland, OR||Japan*||Quantity|
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|Purity / Analysis Method||>98.0%(HPLC)|
|Molecular Formula / Molecular Weight||C__1__9H__1__5NaO__4 = 330.31|
|Physical State (20 deg.C)||Solid|
|Store Under Inert Gas||Store under inert gas|
|Condition to Avoid||Air Sensitive|
|Related CAS RN||81-81-2|
|Reaxys Registry Number||5469050|
|PubChem Substance ID||87560363|
|Merck Index (14)||10038|
|Appearance||White to Almost white powder to crystal|
|Purity(HPLC)||min. 98.0 area%|
|Purity(Nonaqueous Titration)||min. 91.0 %|
|2-Propanol||7.0 to 9.0 %|
|Solubility in water||Completely soluble|
|Solubility (very soluble in)||Alcohol|
|Solubility (slightly sol. in)||Ether,Chloroform|
|Hazard Statements||H300 : Fatal if swallowed.
H360 : May damage fertility or the unborn child.
H370 : Causes damage to organs.
H372 : Causes damage to organs through prolonged or repeated exposure.
H373 : May cause damage to organs through prolonged or repeated exposure.
H412 : Harmful to aquatic life with long lasting effects.
|Precautionary Statements||P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P307 + P311 : IF exposed: Call a POISON CENTER or doctor/ physician.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
|UN Number (DOT-AIR)||UN1544|
|Packing Group (TCI-A)||II|
Warfarin is known to have affinity for Human Serum Albumin (HSA) and to bind (interact) to drug binding site I on HSA. Those were confirmed using our warfarin sodium with Surface Plasmon Resonance (SPR) and a method using fluorescent probes. 【SPR】Dose responses of warfarin to HSA were confirmed by SPR. Biacore, as a SPR biosensor, was used for the assay, according to the user’s guide of the instrument.
Fluorescent Dye Cocktail for Multiplex Drug￢Site Mapping on Human Serum Albumin
High-resolution and high-throughput protocols for measuring drug/human serum albumin interactions using BIACORE
Biosensor Analysis of the Interaction between Immobilized Human Serum Albumin and Drug Compounds for Prediction of Human Serum Albumin Binding Levels
Characterizing a drug's primary binding site on albumin
Structural basis of the drug-binding specificity of human serum albumin
Comparative pharmacokinetics of vitamin K antagonists: warfarin, phenprocoumon and acenocoumarol
Systematic overview of warfarin and its drug and food interactions
Pharmacogenetics of warfarin elimination and its clinical implications
Pharmacogenetics of warfarin: current status and future challenges
Pharmacogenetics of warfarin: regulatory, scientific, and clinical issues
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