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CAS RN: 125995-03-1 | Product Number: A3114

Atorvastatin Lactone


Purity: >95.0%(HPLC)
Synonyms:
  • 5-(4-Fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide
  • Atorvastatin Related Compound H
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25MG
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Product Number A3114
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__3__3H__3__3FN__2O__4 = 540.64  
Physical State (20 deg.C) Solid
Packaging and Container 25MG-Glass Bottle with Plastic Insert (View image)
CAS RN 125995-03-1
Reaxys Registry Number 4303217
PubChem Substance ID 354335148
Merck Index (14) 864
MDL Number

MFCD00899262

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 95.0 area%
Elemental analysis(Nitrogen) 4.70 to 5.70 %
Properties (reference)
Melting Point 161 °C
GHS
Related Laws:
Transport Information:
HS Number 2933.99.7500
Application
Atorvastatin Lactone: An Inactive Metabolite of Atorvastatin

Atorvastatin lactone is an inactive metabolite of atorvastatin [A2476] which is an inhibitor of HMG-CoA reductase used to lower blood cholesterol levels. Reportedly, atorvastatin lactone prevents inhibition of P-glycoprotein in a concentration-dependent manner.

References


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