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CAS RN: 77337-73-6 | Product Number: A2359

Acamprosate Calcium

Purity: >98.0%(HPLC)(N)
  • Calcium 3-Acetamido-1-propanesulfonate
  • 3-Acetamido-1-propanesulfonic Acid Calcium Salt
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Product Number A2359
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__1__0H__2__0CaN__2O__8S__2 = 400.47  
Physical State (20 deg.C) Solid
CAS RN 77337-73-6
Related CAS RN 77337-76-9
Reaxys Registry Number 8945911
PubChem Substance ID 125307900
SDBS (AIST Spectral DB) 52940
Merck Index (14) 17
MDL Number


Appearance White to Almost white powder to crystaline
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Properties (reference)
Melting Point 270 °C
Solubility in water Completely soluble
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
Related Laws:
RTECS# TZ6357000
Transport Information:
HS Number 2924.29.9500
Neuroprotective Effects of Acamprosate Calcium

Acamprosate calcium is a synthetic compound with a chemical structural similar of the endogenous amino acid homotaurine [A2602], and a structural analogue of the amino acid neurotransmitter γ-aminobutyric acid (GABA) [A0282] and the amino acid neuromodulator taurine [A0295]. The precise mechanism is not fully understood, but there is evidence to suggest that acamprosate may interact with glutamate and GABA, excitatory and inhibitory neurotransmitter systems centrally, and has led to the hypothesis that acamprosate restores this balance. Acamprosate calcium is widely used in the treatment of alcohol dependence in clinical. (The product is for research purpose only.)


PubMed Literature

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