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CAS RN: 2353-33-5 | Product Number: A2232

5-Aza-2'-deoxycytidine


Purity:
Synonyms:
  • 5-Aza-1-(2-deoxy-β-D-ribofuranosyl)cytosine
  • Decitabine
Documents:
20MG
$63.00
4   3   6  
100MG
$218.00
5   2   6  

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Product Number A2232
Molecular Formula / Molecular Weight C__8H__1__2N__4O__4 = 228.21  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Heat Sensitive
CAS RN 2353-33-5
Reaxys Registry Number 617982
PubChem Substance ID 160871263
Merck Index (14) 2853
MDL Number

MFCD00043011

Specifications
Appearance White to Almost white powder to crystal
Elemental analysis(Nitrogen) 23.8 to 25.0 %
Properties (reference)
Melting Point 191 °C(dec.)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H341 : Suspected of causing genetic defects.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# XZ3012000
Transport Information:
HS Number 2934.99.9001
Application
An Inhibitor of DNA Methylation

The cytidine analogs 5-aza-2'-deoxycytidine and 5-azacytidine [A2033] are inhibitors of DNA methyltransferases (DNMTs) which catalyze the transfer of a methyl group to DNA. DNA methylation is an epigenetic factor and plays an important role in regulating gene expression. 5-Azacytidine and 5-aza-2'-deoxycytidine are the currently most advanced agents for epigenetic cancer therapies. (The product is for research purpose only.)

References


PubMed Literature


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