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CAS RN: 34369-07-8 | Product Number: A0157

Adenosine 5'-Triphosphate Disodium Salt Hydrate


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 5'-ATP 2Na Hydrate
Documents:
1G
$28.00
9   2   ≥20 
5G
$73.00
6   2   13  
25G
$255.00
5   1   ≥20 

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Product Number A0157
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__0H__1__4N__5Na__2O__1__3P__3·xH__2O = 551.14  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Heat Sensitive
CAS RN 34369-07-8
Related CAS RN 987-65-5
Reaxys Registry Number 3585462
PubChem Substance ID 87561840
Merck Index (14) 155
MDL Number

MFCD00080339

Specifications
Appearance White to Almost white powder to crystaline
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %(calcd.on anh.substance)
abs-ratio(a/b) 0.78 to 0.82(E250/E260)
abs-ratio(2a/2b) 0.13 to 0.17(E280/E260)
Solubility in Water almost transparency
Water max. 12.0 %
Properties (reference)
Specific Rotation -19° (C=3,H2O)
Solubility in water Soluble
GHS
Related Laws:
RTECS# AU7417000
Transport Information:
HS Number 2934.99.9001
Application
Reagent for dysuria model
References

Inhibition of ATP-induced contraction in the guinea-pig urinary bladder in vitro and in vivo

C. Sjögren, K. E. Andersson, Acta Pharmacol. Toxicol. (Copenh). 1979, 44, 221.

Sources of calcium for ATP-induced contractions in rat urinary bladder smooth muscle

M. B. Bhat, S. K. Mishra, V. Raviprakash, Eur. J. Pharmacol. 1989, 164, 163.


Application
Reagent for pain model
References

Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats

M. Okada, T. Nakagawa, M. Minami, M. Satoh, J. Pharmacol. Exp. Ther. 2002, 303, 66.

Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance

T. Nakagawa, K. Wakamatsu, N. Zhang, S. Maeda, M. Minami, M. Satoh, S. Kaneko, Neuroscience 2007, 147, 445.

ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model.

Z. Y. Zhuang, P. Gerner, C. J. Woolf, R. R. Ji, Pain 2005, 114, 149.


PubMed Literature


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