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CAS RN: 129-56-6 | Product Number: A2548


Purity: >95.0%(HPLC)
  • Dibenzo[cd,g]indazol-6(2H)-one
  • SP 600125
14   3  

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.

Product Number A2548
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__1__4H__8N__2O = 220.23  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 129-56-6
Reaxys Registry Number 746890
PubChem Substance ID 253659651
MDL Number


Appearance Light yellow to Yellow to Green powder to crystal
Purity(HPLC) min. 95.0 area%
Elemental analysis(Nitrogen) 12.1 to 13.3 %
Properties (reference)
Melting Point 282 °C
Related Laws:
RTECS# CB4585000
Transport Information:
H.S.code* 2933.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.

PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells

T.C. Ho, S.L. Chen, Y.C. Yang, C.L. Liao, H.C. Cheng, Y.P. Tsao, Cardiovasc. Res. 2007, 76, 213.

Nongenotropic, anti-apoptotic signaling of 1α,25(OH)2-vitamin D3 and analogs through the ligand binding domain of the vitamin D receptor in osteoblasts and osteocytes: MEDIATION BY Src, PHOSPHATIDYLINOSITOL 3-, AND JNK KINASES

A.M. Vertino, C.M. Bula, J.R. Chen, M. Almeida, L. Han, T. Bellido, S. Kousteni, A.W. Norman, S.C. Manolagas, J. Biol. Chem. 2005, 280, 14130.

c-Jun N-Terminal Kinase (JNK) Inhibitor

1)SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

B. L. Bennett, D. T. Sasaki, B. W. Murray, E. C. O’Leary, S. T. Sakata, W. Xu, J. C. Leisten, A. Motiwala, S. Pierce, Y. Satoh, S. S. Bhagwat, A. M. Manning, D. W. Anderson, Proc. Natl. Acad. Sci. USA 2001, 98, 13681.

2)Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125

Y.-S. Heo, S.-K. Kim, C. I. Seo, Y. K. Kim, B.-J. Sung, H. S. Lee, J. I. Lee, S. Y. Park, J. H. Kim, K. Y. Hwang, Y.-L. Hyun, Y. H. Jeon, S. Ro, J. M. Cho, T. G. Lee, C.-H. Yang, EMBO J. 2004, 23, 2185.

3)A mammalian scaffold complex that selectively mediates MAP kinase activation

A. J. Whitmarsh, J. Cavanagh, C. Tournier, J. Yasuda, R. J. Davis, Science 1998, 281, 1671.

4)Scaffold proteins of MAP-kinase modules

D. N. Dhanasekaran, K. Kashef, C. M. Lee, H. Xu, E. P. Reddy, Oncogene 2007, 26, 3185.

5)Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1

S.-H. Yang, A. J. Whitmarsh, R. J. Davis, A. D. Sharrocks, EMBO J. 1998, 17, 1740.

PubMed Literature


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