text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 2627-69-2 | Product Number: A2528

5-Aminoimidazole-4-carboxamide 1-β-D-Ribofuranoside

Purity: >98.0%(HPLC)
  • 5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide
  • Acadesine
5   8  

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.

Product Number A2528
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__9H__1__4N__4O__5 = 258.23  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
CAS RN 2627-69-2
Reaxys Registry Number 38255
PubChem Substance ID 253659575
Merck Index (14) 16
MDL Number


Appearance White to Light yellow to Light red powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 21.20 to 22.00 %
Specific rotation [a]20/D -61.0 to -66.0 deg(C=1、H2O)
Properties (reference)
Melting Point 212 °C
Specific Rotation -63° (C=1,H2O)
Maximum Absorption Wavelength 265(NaOH) nm
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
Transport Information:
H.S.code* 2934.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Acadesine (AICAR): AMP-Activated Protein Kinase Activator

5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside (Acadesine or AICAR) has been extensively used in vitro and in vivo to activate AMP-activated protein kinase (AMPK). AMPK stimulates energy production via glucose and lipid metabolism, whereas it inhibits energy consuming functions, such as protein and cholesterol synthesis. Therefore, acadesine may have applications in treating disorders such as type 2 diabetes and Alzheimer's disease. Recently, it has been shown that acadesine induces leukemia apoptosis. (The product is for research purpose only.)


PubMed Literature

Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number is entered
Analytical Charts
Please enter Lot Number Incorrect Lot Number is entered

The requested analytical chart is not available. Sorry for the inconvenience.

Other Documents