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CAS RN: 56180-94-0 | Product Number: A2485
Acarbose Hydrate
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Purity: >98.0%(HPLC)(N)
Synonyms:
Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 1G |
$100.00
|
12 | 10 |
| 5G |
$342.00
|
≥20 | 5 |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | +173 to +183 deg(C=1、H2O)(calcd.on anh.substance) |
| Water | max. 5.0 % |
Properties (reference)
| Specific Rotation | 176° (C=1,H2O) |
| Solubility in water | Completely soluble |
| Solubility (very slightly) | Ethanol |
GHS
Related Laws:
| RTECS# | LZ7153000 |
Transport Information:
| H.S.code* | 2940.00-000 |
Application
Acarbose: α-Glucosidase Inhibitor
Acarbose, a complex oligosaccharide, is obtained from fermentation processes of a microorganism, Actinoplanes utahensis. Acarbose acts by competitive and reversible inhibition of intestinal α-glucosidases and α-amylase which are enzymes responsible for the metabolite of complex carbohydrates into absorbable monosaccharide units. This action delays the digestion of ingested carbohydrates, thereby resulting in a smaller rise in blood glucose concentration following meals. In contrast to sulfonylureas, acarbose does not enhance insulin secretion. Acarbose is used for the treatment of type 2 diabetes. (The product is for research purpose only.)
References
- Acarbose. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential
- Biotechnology and molecular biology of the α-glucosidase inhibitor acarbose (a review)
- Inhibitory activities of cyanidin and its glycosides and synergistic effect with acarbose against intestinal α-glucosidase and pancreatic α-amylase
- Analysis and determination of anti-diabetes drug acarbose and its structural analogs (a review)
PubMed Literature
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TCIMAIL
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