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CAS RN: 1744-22-5 | Product Number: A2423

Riluzole


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 2-Amino-6-(trifluoromethoxy)benzothiazole
Documents:
5G
$128.00
15   4  
25G
$446.00
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* The storage conditions are subject to change without notice.


Product Number A2423
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__8H__5F__3N__2OS = 234.20  
Physical State (20 deg.C) Solid
CAS RN 1744-22-5
Reaxys Registry Number 748759
PubChem Substance ID 253662378
Merck Index (14) 8223
MDL Number

MFCD00210213

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 116.0 to 120.0 °C
Properties (reference)
Melting Point 118 °C
Solubility in water Insoluble
Solubility (soluble in) Methanol,Acetone,Ether,Dimethylformamide
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H300 : Fatal if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# DL2830000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group II
H.S.code* 2934.20-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Riluzole: A Neuroprotective Agent

Riluzole is a neuroprotective agent that blocks glutamatergic neurotransmission in the neuronal synapse. Riluzole would affect neurons by 3 mechanisms: by inhibiting excitatory L-glutamic acid [G0059] release, inhibiting events following stimulation of excitatory glutamic acid receptors and stabilizing the inactivated state of voltage-dependent sodium channels. Riluzole is mainly used for the treatment of amyotrophic lateral sclerosis (ALS) which would be associated with glutamate excitotoxicity. (The product is for research purpose only.)

References


PubMed Literature


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