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CAS RN: 88519-57-7 | Product Number: A2416

N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide Hydrochloride


Purity: >98.0%(HPLC)(N)
Synonyms:
  • W-13 Hydrochloride
Documents:
25MG
€ 32,00
2   8  
500MG
€ 316,00
3   11  

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*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number A2416
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__1__4H__1__7ClN__2O__2S·HCl = 349.27  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Light Sensitive,Heat Sensitive
CAS RN 88519-57-7
Related CAS RN 81705-04-6
PubChem Substance ID 135727209
MDL Number

MFCD00058030

Specifications
Appearance Light orange to Light red powder to crystalline
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Melting point 235.0 to 239.0 °C
Properties (reference)
Melting Point 237 °C
GHS
Related Laws:
Transport Information:
HS Number 2935909099
Application
Studies on Calmodulin Inhibitory Activity
References

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

D. S. Bredt, S. H. Snyder, Proc. Natl. Acad. Sci. U.S.A. 1990, 87, 682.

Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor

K. J. Padmanabhan, D. L. Kilby, H. J. Cohen, M. S. Currie, J. B. Weinberg, J. Leukocyte Biol. 1992, 51, 496.

Inhibition of volume-activated I- and taurine efflux from HeLa cells by P-glycoprotein blockers correlates with calmodulin inhibition

J. Kirk, K. Kirk, J. Biol. Chem. 1994, 269, 29389.

Membrane-permeable Calmodulin Inhibitors (e.g. W-7/W-13) Bind to Membranes, Changing the Electrostatic Surface Potential: Dual effect of W-13 on epidermal growth factor receptor activation

P. Sengupta, M. J. Ruano, F. Tebar, U. Golebiewska, I. Zaitseva, C. Enrich, S. McLaughlin, A. Villalobo, J. Biol. Chem. 2007, 282, 8474.


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