CAS RN: 632-85-9 | Product Number: W0010
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|Purity / Analysis Method||>98.0%(HPLC)|
|Molecular Formula / Molecular Weight||C__1__6H__1__2O__5 = 284.27|
|Physical State (20 deg.C)||Solid|
|Condition to Avoid||Heat Sensitive|
|Reaxys Registry Number||287152|
|PubChem Substance ID||354335738|
|Appearance||Light orange to Yellow to Green powder to crystal|
|Purity(HPLC)||min. 98.0 area%|
|Melting point||205.0 to 209.0 °C|
|Melting Point||207 °C|
|Maximum Absorption Wavelength||319(EtOH) nm|
Wogonin is an O-methylated monoflavonoid found in Scutellaria baicalensis which is one of the most popular and multi-purpose herb used in China traditionally for treatment of various diseases1,2). Wogonin is also one of the active ingredients of Sho-Saiko-To, a Japanese herbal supplement3). It has been reported that wogonin exerts anti-oxidant1), anti-cancer4), anti-inflammatory4,5), anti-viral4,6) and neuroprotective effects7). For your reference, a glycoside of wogonin is wogonoside [W12]. (The product is for research purpose only.)
1)Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi
2)Characterization of flavonoids in the traditional Chinese herbal medicine-Huangqin by liquid chromatography coupled with electrospray ionization mass spectrometry
3)Effects of Sho-saiko-to, a Japanese herbal medicine, on hepatic fibrosis in rats
4)New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin (a review)
5)Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide
6)Anti-hepatitis B virus activity of wogonin in vitro and in vivo
7)Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia
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