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CAS RN: 81403-68-1 | Product Number: A2591

Alfuzosin Hydrochloride

Purity: >98.0%(HPLC)
  • N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)(methyl)amino]propyl]tetrahydro-2-furancarboxamide Hydrochloride
  • 4-Amino-6,7-dimethoxy-2-[methyl[3-[(tetrahydro-2-furoyl)amino]propyl]amino]quinazoline Hydrochloride
5   ≥20 
3   7  

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Product Number A2591
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__9H__2__7N__5O__4·HCl = 425.91  
Physical State (20 deg.C) Solid
CAS RN 81403-68-1
Related CAS RN 81403-80-7
Reaxys Registry Number 6034829
PubChem Substance ID 253659564
Merck Index (14) 238
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 96.0 %
Properties (reference)
Melting Point 229 °C(dec.)
Related Laws:
RTECS# LT9965475
Transport Information:
HS Number 2934999090
Alfuzosin, A Selective α1-Adrenoceptor Antagonist

Alfuzosin, a selective α1-adrenoceptor antagonist in the lower urinary tract

F. Lefèvre-Borg, S. E. O'Connor, H. Schoemaker, P. E. Hicks, J. Lechaire, E. Gautier, F. Pierre, C. Pimoule, P. Manoury, S. Z. Langer, Br. J. Pharmacol. 1993, 109, 1282.

Use of recombinant α1-adrenoceptors to characterize subtype selectivity of drugs for the treatment of prostatic hypertrophy

R. Foglar, K. Shibata, K. Horie, A. Hirasawa, G. Tsujimoto, Eur. J. Pharmacol. Mol. Pharmacol. 1995, 288, 201.

Synthesis and antihypertensive activity of a series of 4-amino-6,7-dimethoxyquinazoline derivatives

P. M. Manoury , J. L. Binet , A. P. Dumas , F. Lefevre-Borg , I. Cavero, J. Med. Chem. 1986, 29, 19.

Alfuzosin: an α1-receptor blocker for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia

M. M. Elhilali, Expert Opin. Pharmacother. 2006, 7, 583.

Alfuzosin delays cardiac repolarization by a novel mechanism

A. E. Lacerda, Y. A. Kuryshev, Y. Chen, M. Renganathan, H. Eng, S. J. Danthi, J. W. Kramer, T. Yang, A. M. Brown, J. Pharmacol. Exp. Ther. 2008, 324, 427.

PubMed Literature

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