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CAS RN: 81403-68-1 | Product Number: A2591

Alfuzosin Hydrochloride


Purity: >98.0%(HPLC)
Synonyms:
  • N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)(methyl)amino]propyl]tetrahydro-2-furancarboxamide Hydrochloride
  • 4-Amino-6,7-dimethoxy-2-[methyl[3-[(tetrahydro-2-furoyl)amino]propyl]amino]quinazoline Hydrochloride
Documents:
100MG
€17.00
5   ≥20 
1G
€81.00
3   7  

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*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number A2591
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__9H__2__7N__5O__4·HCl = 425.91  
Physical State (20 deg.C) Solid
CAS RN 81403-68-1
Related CAS RN 81403-80-7
Reaxys Registry Number 6034829
PubChem Substance ID 253659564
Merck Index (14) 238
MDL Number

MFCD00879135

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 96.0 %
Properties (reference)
Melting Point 229 °C(dec.)
GHS
Related Laws:
RTECS# LT9965475
Transport Information:
HS Number 2934999090
Application
Alfuzosin, A Selective α1-Adrenoceptor Antagonist
References

Alfuzosin, a selective α1-adrenoceptor antagonist in the lower urinary tract

F. Lefèvre-Borg, S. E. O'Connor, H. Schoemaker, P. E. Hicks, J. Lechaire, E. Gautier, F. Pierre, C. Pimoule, P. Manoury, S. Z. Langer, Br. J. Pharmacol. 1993, 109, 1282.

Use of recombinant α1-adrenoceptors to characterize subtype selectivity of drugs for the treatment of prostatic hypertrophy

R. Foglar, K. Shibata, K. Horie, A. Hirasawa, G. Tsujimoto, Eur. J. Pharmacol. Mol. Pharmacol. 1995, 288, 201.

Synthesis and antihypertensive activity of a series of 4-amino-6,7-dimethoxyquinazoline derivatives

P. M. Manoury , J. L. Binet , A. P. Dumas , F. Lefevre-Borg , I. Cavero, J. Med. Chem. 1986, 29, 19.

Alfuzosin: an α1-receptor blocker for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia

M. M. Elhilali, Expert Opin. Pharmacother. 2006, 7, 583.

Alfuzosin delays cardiac repolarization by a novel mechanism

A. E. Lacerda, Y. A. Kuryshev, Y. Chen, M. Renganathan, H. Eng, S. J. Danthi, J. W. Kramer, T. Yang, A. M. Brown, J. Pharmacol. Exp. Ther. 2008, 324, 427.


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