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CAS RN: 56180-94-0 | Product Number: A2485

Acarbose Hydrate


Purity: >98.0%(HPLC)(N)
Synonyms:
Documents:
1G
€60.30
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5G
€166.50
3   ≥20 

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Product Number A2485
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__2__5H__4__3NO__1__8 = 645.61  
Physical State (20 deg.C) Solid
CAS RN 56180-94-0
Reaxys Registry Number 4898350
PubChem Substance ID 160871251
Merck Index (14) 18
MDL Number

MFCD00869592

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %(calcd.on anh.substance)
Specific rotation [a]20/D +173 to +183 deg(C=1、H2O)(calcd.on anh.substance)
Water max. 5.0 %
Properties (reference)
Specific Rotation 176° (C=1,H2O)
Solubility in water Completely soluble
Solubility (very slightly) Ethanol
GHS
Related Laws:
EC Number 260-030-7
RTECS# LZ7153000
Transport Information:
HS Number 2940000080
Application
Acarbose: α-Glucosidase Inhibitor

Acarbose, a complex oligosaccharide, is obtained from fermentation processes of a microorganism, Actinoplanes utahensis. Acarbose acts by competitive and reversible inhibition of intestinal α-glucosidases and α-amylase which are enzymes responsible for the metabolite of complex carbohydrates into absorbable monosaccharide units. This action delays the digestion of ingested carbohydrates, thereby resulting in a smaller rise in blood glucose concentration following meals. In contrast to sulfonylureas, acarbose does not enhance insulin secretion. Acarbose is used for the treatment of type 2 diabetes. (The product is for research purpose only.)

References


PubMed Literature


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